Cosimo Ducani |
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Contact |
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Room
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Ha308
+ 44 121 41 48068
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Status
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Marie Curie Early Stage Researcher |
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Date joined group
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19th January 2009 |
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Research interest
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Study of interaction of metal compound with DNA and enzymes. Synthesis and characterization of new platinum drug. |
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Qualifications |
- July 2004: Degree in Biotechnologies. University of Salento (Lecce, Italy). -October 2006: Master degree in Biotechnological Sciences (Lecce, Italy).Thesis dissertation title: Possible involvement of free nucleotide in the mechanism of action of cisplatin. January 2006: PhD in Applied Synthetic and Enzymatic Chemistry. University of Bari. (Bari, Italy)
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Conferences
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- XXXVI Scientific Meeting of the Inorganic Division of the Italian Chemistry Society (SCI). Lecce 1-5 September (O40): Benedetti Michele, Ducani Cosimo, Migoni Danilo, Antonucci Daniela, Vecchio Vita M., Romano Alessandro, Verri Tiziano, Fanizzi Francesco P. (2008) Possible incorporation in DNA of free N7-platinated guanines by DNA polymerases. -Bioinorganic National School for PhD student. Napoli, Italy 14-16 September (04): Benedetti, Michele; Ducani, Cosimo; Migoni, Danilo; Antonucci, Daniela; Vecchio, Vita M.; Ciccarese, Antonella; Romano, Alessandro; Verri, Tiziano; Ciccarella, Giuseppe; Fanizzi, Francesco P. (2008) Possible incorporation in DNA of free N7-platinated guanines by DNA polymerases.
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Publications |
- BENEDETTI M, DUCANI C., MIGONI D, ANTONUCCI D, VECCHIO V. M, ROMANO A, VERRI T, FANIZZI F. P (2009). Possible Incorporation of Free N7 -Platinated Guanines in DNA by DNA Polymerases, Relevance for the Cisplatin Mechanism of Action. In: BONETTI A.; LEONE R.; MUGGIA F. M.; HOWELL S. B.. Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy. p. 125-132, ISBN/ISSN: 978-1-60327-458-6, doi: 10.1007/978-1-60327-459-3_17
- BENEDETTI M, DUCANI C., MIGONI D, ANTONUCCI D, VECCHIO V.M, CICCARESE A, ROMANO A, VERRI T, CICCARELLA G. AND FANIZZI F.P (2008). Experimental evidence that a DNA polymerase can incorporate N7-platinated guanines to give a platinated DNA. ANGEWANDTE CHEMIE. INTERNATIONAL EDITION; p. 507-510, ISSN: 1433-7851
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